Monday, April 13, 2009

Viruses that are a little standoffish

Adenoviruses are excellent vectors because they pop their genes into cells
regardless of whether cell division is occurring. Adenoviruses have been both
promising and problematic. On the one hand, these viruses are really good at
getting into host cells. On the other hand, adenoviruses tend to excite a strong
immune response — the patient’s body senses the virus as a foreign particle
and fights it. To combat the immune reaction, researchers have worked to
delete the genes that make adenoviruses easy for the host to recognize.

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